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SW155246
Item number: TGM-T8967-100mg
Description: SW155246 is a potent and selective inhibitor of DNMT1 (DNA methyltransferase 1, IC50 of 1.2 µM). SW155246 induces re-expression of the tumor suppressor geneRASSF1 in A549 cells. Target: DNA Methyltransferase. Smiles: Oc1ccc(NS(=O)(=O)c2ccc(Cl)c(c2)[N+]([O-])=O)c2ccccc12. References: Medina-Franco J , O...
| Application: | DNMT1 antagonist |
| CAS | 420092-79-1 |
| MW: | 378.79 D |
From 42.00€
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SW155246
Item number: Cay21865-5
SW155246 is an inhibitor of DNA methyltransferase 1 (DNMT1, IC50 = 1.2 µM). It is selective for human DNMT1 over murine DNMT3 (IC50 = 38 µM). SW155246 inhibits HeLa and A549 tumor cell growth in a redox-independent manner (IC50s = 8-20 µM). It also inhibits genomic methylation in HeLa cells when used at...
| Keywords: | 4-chloro-N-(4-hydroxy-1-naphthalenyl)-3-nitro-benzenesulfonamide |
| Application: | DNMT1 antagonist |
| CAS | 420092-79-1 |
| MW: | 378.8 D |
From 54.00€
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