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Lenvatinib
Lenvatinib

Item number: Cay19375-5

Lenvatinib is an inhibitor of the receptor tyrosine kinases VEGF receptor 2 (VEGFR2) and VEGFR3 (IC50s = 4 and 5.2 nM, respectively). It also inhibits the related kinases VEGFR1, FGFR1, PDGFRalpha, PDGFRbeta and Kit (IC50s = 22, 46, 51, 39, and 100 nM, respectively). Lenvatinib (30 mg/kg, twice per day) reduces...
Keywords: E-7080, ER-203492-00, 4-[3-chloro-4-[[(cyclopropylamino)carbonyl]amino]phenoxy]-7-methoxy-6-quinolinecarboxamide
Application: VEGFR / FGFR / PDGFR inhibitor
CAS 417716-92-8
MW: 426.9 D
From 43.00€ *
Review
E-7080
E-7080

Item number: SYN-1038-M001

Soluble in DMSO or ethanol. E7080 is an orally active inhibitor of multiple receptor tyrosine kinases including VEGF, FGF and SCF receptors. It is most potent against VEGFR2(KDR)/VEGFR3(Flt-4), with IC(50) values of 4nM and 5.2nM respectively. Target: FGFR - VEGFR - SCF , Kinase Group: RTK , Substrate: Tyrosine
Keywords: E-7080
Application: VEGFR2 /VEGFR3 inhibitor
CAS 417716-92-8
MW: 426,9 D
From 119.00€ *
Review