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Item number: Cay41592-10

Tocainide is an antiarrhythmic agent and a derivative of the local anesthetic lidocaine. It inhibits voltage-gated sodium channel 1.4 (Nav1.4) in HEK293 cells expressing the human channel (IC50s = 699 and 182 µM at 0.1 and 10 Hz, respectively). Tocainide reduces the action potential duration at 50% repolarization in...

Keywords:	(R,S)-Tocainide, W-36095, 2-amino-N-(2,6-dimethylphenyl)-propanamide
Application:	Antiarrhythmic agent, sodium channel blocker
CAS	41708-72-9
MW:	192.3 D

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