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N-desmethyl Bendamustine
N-desmethyl Bendamustine

Item number: Cay27171-1

N-desmethyl Bendamustine is an active metabolite of the DNA alkylating agent bendamustine (Cay-23693). N-desmethyl Bendamustine is formed through demethylation of the benzimidazole ring in bendamustine by the cytochrome P450 (CYP) isoform CYP1A2. It inhibits proliferation of non-cancerous peripheral blood leukocytes...
Keywords: nor-Bendamustine, 6-[bis(2-chloroethyl)amino]-1H-benzimidazole-2-butanoic acid
Application: Alkylating agent
CAS 41515-13-3
MW: 344.2 D
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