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Palovarotene
Palovarotene

Item number: Cay28460-5

Palovarotene an orally bioavailable retinoic acid receptor gamma (RARgamma) agonist. It increases retinoic acid response element (RARE) activity and decreases NF-kappaB activity induced by IL-1beta in primary mouse stromal cells in reporter assays when used at a concentration of 60 nM. Palovarotene (10 nM) inhibits...
Keywords: Ro 3300074, 4-[(1E)-2-[5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-3-(1H-pyrazol-1-ylmethyl)-2-naphthalenyl]ethenyl]-benzoic acid
Application: Retinoic acid receptor gamma agonist
CAS 410528-02-8
MW: 414.5 D
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