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Item number: TGM-T17238-100mg

Description: VU0152100 is an effective and selective allosteric potentiator of M4 mAChR (EC50: 380 ± 93 nM). Target: AChR. Smiles: COc1ccc(CNC(=O)c2sc3nc(C)cc(C)c3c2N)cc1. References: Brady AE, et al. Centrally active allosteric potentiators of the M4 muscarinic acetylcholine receptor reverse amphetamine-induced...

Keywords:	VU152100
Application:	Muscarinic M4 receptor positive allosteric modulator
CAS	409351-28-6
MW:	341.43 D

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VU0152100

Item number: Cay32968-10

VU0152100 is a positive allosteric modulator of M4 muscarinic acetylcholine receptors. It potentiates calcium mobilization induced by acetylcholine (ACh) in CHO-K1 cells expressing the rat M4 receptor with an EC50 value of 380 nM. VU0152100 is selective for M4 over M1, M2, M3 and M5 receptors, as well as a panel of...

Keywords:	3-amino-N-[(4-methoxyphenyl)methyl]-4,6-dimethyl-thieno[2,3-b]pyridine-2-carboxamide
Application:	Muscarinic M4 receptor positive allosteric modulator
CAS	409351-28-6
MW:	341.4 D

From 126.00€ *

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