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Salubrinal
Salubrinal

Item number: TGM-T3045-2mg

Description: Salubrinal, a phosphatases (PP1) inhibitor(IC50=1.7 µM), exhibits function on the eukaryotic translation initiation factor 2 subunit (eIF2alpha). Target: HSV, Apoptosis, PERK, Phosphatase, Autophagy. Smiles: ClC(Cl)(Cl)C(NC(=S)NC1=CC=CC2=CC=CN=C12)NC(=O)\C=C\C1=CC=CC=C1. References: Boyce M, et al....
Application: eIF2alpha dephosphorylation (PP1) inhibitor
CAS 405060-95-9
MW: 479.81 D
From 37.00€ *
Review
Salubrinal
Salubrinal

Item number: Cay14735-1

Salubrinal is a selective phosphatase inhibitor that prevents dephosphorylation of eukaryotic translation initiation factor 2 subunit alpha (eIF2alpha), protecting PC12 cells from endoplasmic reticulum stress-mediated apoptosis (EC50 = 15 µM). It appears to block the action of protein phosphatase 1 (PP1) on...
Keywords: (2E)-3-phenyl-N-[2,2,2-trichloro-1-[[(8-quinolinylamino)thioxomethyl]amino]ethyl]-2-propenamide
Application: eIF2alpha dephosphorylation (PP1) inhibitor
CAS 405060-95-9
MW: 479.8 D
From 36.00€ *
Review