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Panobinostat
Item number: Cay13280-5
Panobinostat is a pan-inhibitor of histone deacetylases (HDACs, Kis = 0.6-31 nM for HDAC1-11). It inhibits growth in a panel of 37 human or mouse lung cancer cell lines, including small cell lung cancer (SCLC), non-small cell lung cancer (NSCLC), and mesothelioma cells (IC50s = 4-175, 5-310, and 5-470 nM,...
| Keywords: | LBH-589, (2E)-N-hydroxy-3-[4-[[[2-(2-methyl-1H-indol-3-yl)ethyl]amino]methyl]phenyl]-2-propenamide |
| Application: | HDAC inhibitor |
| CAS | 404950-80-7 |
| MW: | 349.4 D |
From 40.00€
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LBH-589
Item number: LKT-L0528.25
HDAC1/2/3/11 inhibitor.
| Keywords: | LBH589, Panobinostat |
| Application: | Histone deacetylases (HDACs) inhibitor |
| CAS | 404950-80-7 |
| MW: | 349.43 D |
From 102.00€
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LBH-589 (Panobinostat, NVP-LBH589)
Item number: L1535.10
Panobinostat, a histone deacetylase inhibitor, is being tested in humans against cutaneous T cell lymphoma, prostate cancer, myelodysplastic syndromes, breast cancer, chronic myelogenous leukemia, and other types of malignant disease. Panobinostat inhibited histone deacetylase and induced acetylation of histone H3...
| CAS | 404950-80-7 |
From 116.00€
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