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Item number: Cay18740-1

Cyclin-dependent kinases (Cdks) are key regulators of cell cycle progression and are therefore promising targets for cancer therapy. Cdk1/5 Inhibitor is a pyrazolo [3,4-b] quioxaline that inhibits Cdk1/cyclin B and Cdk5/p25 (IC50s = 600 and 400 nM, respectively). It less potently inhibits GSK3beta (IC50 = 1 µM) and...

Keywords:	Cyclin-dependent kinase 1/5 Inhibitor, NSC 693868, 1H-pyrazolo[3,4-b]quinoxalin-3-amine
Application:	Cdk1/cyclin B inhibitor, Cdk5/p25 inhibitor
CAS	40254-90-8
MW:	185.2 D

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