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Item number: TGM-T15634-100mg

Description: JYL 1421 (SC 0030) is an antagonist of TRPV1 receptor (IC50 = 8 nM). Target: TRP/TRPV Channel. Smiles: CC(C)(C)c1ccc(CNC(=S)NCc2ccc(NS(C)(=O)=O)c(F)c2)cc1. References: Jakab B, et al. Pharmacological characterization of the TRPV1 receptor antagonist JYL1421 (SC0030) in vitro and in vivo in the rat. Eur...

Keywords:	SC 0030
Application:	Selective TRPV1 receptor antagonist
CAS	401907-26-4
MW:	423.57 D

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JYL1421

Item number: Cay20458-500

JYL1421 is an antagonist of transient receptor potential vanilloid 1 (TRPV1). It inhibits calcium uptake induced by capsaicin (Cay-92350, Cay-10010743) in CHO cells expressing rat TRPV1 (EC50 = 9.2 nM). JYL1421 inhibits capsaicin-induced release of the neuropeptides somatostatin, substance P (Cay-24035), and...

Keywords:	N-[4-[[[[[[4-(1,1-dimethylethyl)phenyl]methyl]amino]thioxomethyl]amino]methyl]-2-fluorophenyl]-methanesulfonamide
Application:	Selective TRPV1 receptor antagonist
CAS	401907-26-4
MW:	423.6 D

From 66.00€ *

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