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Item number: Cay27863-1

STX140 is an estrogen sulfamate with anticancer activities. It inhibits steroid sulfatase with IC50 values of 39 and 0.5 nM in placental microsomes and MCF-7 cancer cells, respectively. STX140 also binds to carbonic anhydrase IX and II (Kis = 70 and 270 nM, respectively). It inhibits bovine brain tubulin assembly in...

Keywords:	2-MeOE2bisMATE, 2-Methoxyestradiol-bis-sulphamate, 2-methoxy-estra-1,3,5(10)-triene-3,17beta-diol, disulfamate
Application:	Anticancer agent, estrogen sulfamate, steroid sulfatase inhibitor
CAS	401600-86-0
MW:	460.6 D

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