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Triamterene
Item number: TGM-T0843-1mL
Description: Triamterene is a barosensitive epithelial sodium channel (ENaC) blocker with a diuretic effect. It can also act as an inhibitor of the TGR5 receptor, reducing GLP-1 secretion and cAMP level increases induced by TGR5 activation in a dose-dependent manner. Target: GPCR19, Sodium Channel. Smiles:...
| Keywords: | SKF8542, Ademine |
| CAS | 396-01-0 |
| MW: | 253.26 D |
From 38.00€
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Triamterene
Item number: Cay21242-1
Triamterene is an inhibitor of the epithelial sodium channel (ENaC, IC50 = 4.5 µM for the rat channel). In vivo, triamterene (0.5-32 mg/animal) enhances sodium secretion and decreases potassium secretion in adrenalectomized rats. Formulations containing triamterene have been used in the treatment of edema. This...
| Keywords: | 2,4,7-Triamino-6-phenylpteridine, NSC 77625, SKF 8542, 6-phenyl-2,4,7-pteridinetriamine |
| Application: | Epithelial sodium channel blocker |
| CAS | 396-01-0 |
| MW: | 253.3 D |
From 28.00€
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Triamterene
Item number: Cay22486-1
Triamterene (Cay-22486) is an analytical reference standard that is categorized as a pteridine. Triamterene is an inhibitor of the epithelial sodium channel (ENaC) that increases renal sodium excretion and decreases potassium excretion. It inhibits rat ENaC with an IC50 value of 4.5 µM. Diuretics, including...
| Keywords: | 2,4,7-Triamino-6-phenylpteridine, NSC 77625, SKF 8542, 6-phenyl-2,4,7-pteridinetriamine |
| Application: | Analytical reference standard, pteridine, diuretic, ENaC inhibitor |
| CAS | 396-01-0 |
| MW: | 253.3 D |
From 61.00€
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