4 products were found matching "391210-10-9"!
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PD 0325901
Item number: Cay13034-25
The dual specific threonine/tyrosine kinase MEK is a key component of the RAS/RAF/MEK/ERK signaling pathway that is frequently activated in human tumors. PD 0325901 is a potent MEK inhibitor that suppresses phosphorylation of ERK in mouse colon 26 tumors with an IC50 value of 0.33 nM. Suppression of ERK activation...
| Keywords: | N-[(2R)-2,3-dihydroxypropoxy]-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]-benzamide |
| Application: | MEK inhibitor |
| CAS | 391210-10-9 |
| MW: | 482.2 D |
From 59.00€
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Mirdametinib
Item number: TGM-T6189-100mg
Description: Mirdametinib (PD325901) is an MEK inhibitor (IC50=0.33 nM) with selective, non-ATP-competitive, and oral activity. Mirdametinib exhibits antitumor activity by inhibiting p-ERK1/2 expression and inducing apoptosis. Target: Autophagy, MEK, Apoptosis. Smiles:...
| Keywords: | PD0325901, PD325901 |
| Application: | Targets mitogen-activated protein kinase kinase 1 [EC:2.7.12.2] (MAP2K1, MEK1) |
| CAS | 391210-10-9 |
| MW: | 482.19 D |
From 46.00€
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PD 0325901
Item number: AG-CR1-3711-M001
White to off-white solid. Soluble in DMSO (20mg/ml) or ethanol (15mg/ml). Chemical. CAS: 391210-10-9. Formula: C16H14F3IN2O4. MW: 482.2. PD 0325901 is a potent and selective non-ATP competitive orally active MEK1 and MEK2 inhibitor. In comparison to the CI-1040 MEK inhibitor that PD 0325901 has a greater potency of...
| Keywords: | Mirdametinib, N-[(2R)-2,3-dihydroxypropoxy]-3,4-difluoro-2-[(2-fluoro-4-iodophenyl)amino]-benzamide |
| CAS | 391210-10-9 |
| MW: | 482,2 D |
From 28.00€
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PD325901
Item number: LKT-P1202.100
A potent inhibitor of MEK, a key component of the Mitogen activated protein kinase (MAPK) cascade. It has been found to inhibit tumor cell growth, has antiangiogenic and antiproliferative activities.
| Application: | MEK inhibitor |
| CAS | 391210-10-9 |
| MW: | 482,19 D |
From 202.00€
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