3 products were found matching "383432-38-0"!
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CP-724714
Item number: TGM-T4014-100mg
Description: CP-724714 (CP724714) is an effective and selective HER2/ErbB2 inhibitor (IC50: 10 nM), >640-fold selectivity against EGFR, Abl, InsR, PDGFR, IRG-1R, Src, VEGFR2, c-Met etc. Target: EGFR, Apoptosis. Smiles: COCC(=O)NC\C=C\c1ccc2ncnc(Nc3ccc(Oc4ccc(C)nc4)c(C)c3)c2c1. References: Jani JP, et al. Discovery...
| Keywords: | CP 724714, CP724714 |
| Application: | ErbB2 inhibitor |
| CAS | 383432-38-0 |
| MW: | 469.54 D |
From 37.00€
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CP-724714
Item number: SYN-1033-M010
Soluble in DMSO or ethanol. CP-724714 is an oral, selective and potent ErbB-2 (HER2) kinase inhibitor with an IC(50) of 10 nM. It has >640-fold selectivity for ErbB-2 (HER2) over EGFR, InsR, IRG-1R, PDGFR, VEGFR2, Abl, Src, c-Met. Target: HER2 , Kinase Group: RTK , Substrate: Tyrosine
| Keywords: | CP724714 |
| Application: | HER2 inhibitor |
| CAS | 383432-38-0 |
| MW: | 469,5 D |
From 106.00€
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CP 724,714
Item number: Cay19172-1
CP 724,714 is a selective inhibitor of HER2/ErbB2 with an IC50 value of 10 nM. It demonstrates greater than 640-fold selectivity against EGFR, InsR, IRG-1R, PDGFR, VEGFR2, Abl, Src, and c-Met. CP 724,714 has been shown to inhibit the proliferation of ErbB2-amplified cells, including BT474 and SK-BR-3 with IC50...
| Keywords: | 2-methoxy-N-[(2E)-3-[4-[[3-methyl-4-[(6-methyl-3-pyridinyl)oxy]phenyl]amino]-6-quinazolinyl]-2-propen-1-yl]-acetamide |
| Application: | ErbB2 inhibitor |
| CAS | 383432-38-0 |
| MW: | 469.5 D |
From 50.00€
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