Description: Ganglioside GM1, a member of the ganglioside family, serves as a functional tissue receptor for Cholera Toxin1 [1] and is utilized in neurological disease research. Smiles: CCCCCCCCCC...

Isolated from bovine brain. Gangliosides are acidic glycosphingolipids that form lipid rafts in the outer leaflet of the cell plasma membrane, especially in neuronal cells in the central nervous system. They participate in cellular proliferation, differentiation, adhesion, signal transduction, cell-to-cell...

Ganglioside GM1 is a monosialylated ganglioside and the prototypic ganglioside for those containing one sialic acid residue. It is found in a large variety of cells, including immune cells and neurons, and is enriched in lipid rafts in the cell membrane. It associates with growth factor receptors, including TrkA,...

A member of the family of glycosphingolipids, monosialoanglioside acts as a receptor and antigen for cholera toxin. GM1 ganglioside, one of the glycosphingolipids widely distributed in all tissues, occurs in highest concentrations in the central nervous system. It is primarily located in the outer surface of the...