Description: Ribavirin (Tribavirin) is a synthetic nucleoside analog of ribofuranose with activity against hepatitis C virus and other RNA viruses. Target: DNA/RNA Synthesis, HCV Protease, Dehydrogenase, Antibiotic, AChR, RSV. Smiles: NC(=O)C1=NN(C=N1)[C@@H]1O[C@H](CO)[C@@H](O)[C@H]1O. References: Aljabr W, et...

A synthetic, broad-spectrum antiviral nucleoside found to have antitumor activity on L1210 leukemia in mice. It regulates signal transduction in human ovarian cancer cells.

Soluble in DMSO (15mg/ml) or DMF (15mg/ml). Ribavirin is a guanosine analog with broad-spectrum antiviral properties against DNA and RNA viruses, including coronavirus SARS, respiratory syncytial virus, several hemorrhagic fever viruses, hepatitis C (HCV) and influenza. It is also tested for SARS-CoV-2. It acts as...

Ribavirin is an antiviral guanosine nucleoside analog. Upon entry into cells, ribavirin is metabolized to an active triphosphate form that induces viral RNA chain termination and inhibits viral polymerases. It reduces replication in a panel of seven RNA and four DNA viruses in Vero cells (EC50s = 2-95 µg/ml)....