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Item number: Cay39844-10

Metoclopramide is a dual antagonist of the serotonin (5-HT) receptor subtype 5-HT3 and dopamine D2 receptor (IC50s = 308 and 483 nM, respectively). It also reversibly inhibits acetylcholinesterase (AChE) isolated from human postmortem caudate nucleus (Kis = 9.3 and 82 µM for competitive and non-competitive...

Keywords:	4-amino-5-chloro-N-[2-(diethylamino)ethyl]-2-methoxy-benzamide
Application:	Dual 5-HT3 / dopamine D2 receptor antagonist
CAS	364-62-5
MW:	299.8 D

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