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Item number: Cay40649-10

Dimethindene is a histamine H1 receptor antagonist (Ki = 1.5 nM). It is selective for histamine H1 receptors over M1 muscarinic acetylcholine receptors (mAChRs) and the serotonin (5-HT) receptor subtype 5-HT2A (Kis = 64 and 2,400 nM, respectively). In vivo, dimethindene (0.1 mg/kg), alone or in combination with the...

Keywords:	Dimetindene, NSC 107677, SU 6518, N,N-dimethyl-3-[1-(2-pyridinyl)ethyl]-1H-indene-2-ethanamine, 2Z-butenedioate
Application:	Histamine H1 receptor antagonist
CAS	3614-69-5
MW:	408.5 D

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