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Sergliflozin A
Item number: Cay14342-1
Sergliflozin A is an inhibitor of sodium-glucose cotransporter 2 (SGLT2, Ki = 2.39 nM for the human transporter) and an active metabolite of sergliflozin etabonate. It is formed from sergliflozin etabonate by esterases and selectively inhibits SGLT2 over SGLT1 (Ki = 708 nM for the human transporter). Co-infusion of...
| Keywords: | 2[(4methoxyphenyl)methyl]phenyl, beta-D-glucopyranoside |
| Application: | SGLT2 (SLC5A2, sodium/glucose cotransporter) inhibitor, active sergliflozin etabonate metabolite |
| CAS | 360775-96-8 |
| MW: | 376.4 D |
From 67.00€
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Sergliflozin A
Item number: TGM-T68174-100mg
Description: Sergliflozin A is a selective SGLT2 inhibitor that induces diabetes in a dose-dependent manner. It reduces hyperglycemia. Target: SGLT. Smiles: O(C1=C(CC2=CC=C(OC)C=C2)C=CC=C1)[C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O. References: Pajor AM, et al. Inhibitor binding in the human renal low- and...
| CAS | 360775-96-8 |
| MW: | 376.4 D |
From 114.00€
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