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Item number: Cay40428-10

AA43279 is an activator of voltage-gated sodium channel 1.1 (Nav1.1, EC50 = 9.5 µM in a patch-clamp assay using HEK293 cells expressing the human channel). It is selective for Nav1.1 over Nav1.4 and Nav1.7 at 30 µM but also activates Nav1.2, Nav1.5, and Nav1.6 (EC50s = 22.8, 14.4, and 11.6 µM, respectively). AA43279...

Keywords:	3-amino-5-(4-methoxyphenyl)-2-thiophenecarboxamide
Application:	Nav1.1 activator
CAS	354812-16-1
MW:	248.3 D

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