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IKK2-IN-4
Item number: TGM-T36524-100mg
Description: IKK2-IN-4(IKK2 Inhibitor VI) is a highly potent IKK-2 inhibitor with an IC50 value of 25 nM. IKK2-IN-4 inhibited the production of TNF-alpha in PBMC induced by LPS. Target: IkappaB/IKK, TNF. Smiles: N(C(N)=O)C=1SC(=CC1C(N)=O)C2=CC=CC=C2. References: Baxter A, et, al. Hit-to-lead studies: the discovery...
| Keywords: | 5-Phenyl-2-ureidothiophene-3-carboxylic Acid Amide, IKK2 Inhibitor IV |
| Application: | Potent, cell-permeable, reversible IKKbeta inhibitor |
| CAS | 354811-10-2 |
| MW: | 261.3 D |
From 192.00€
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IKK2 Inhibitor VI
Item number: Cay17276-500
Inhibitor of NF-kappaB kinase 2 (IKK2, also known as IKKbeta) acts as part of an IKK complex in the canonical NF-kappaB pathway, phosphorylating inhibitors of NF-kappaB (IkappaBs) to initiate signaling. NF-kappaB signaling can also occur through a non-canonical, IKK/IkappaB-independent pathway. IKK2 Inhibitor VI is...
| Keywords: | 5-Phenyl-2-ureidothiophene-3-carboxylic Acid Amide, 2-[(aminocarbonyl)amino]-5-phenyl-3-thiophenecarboxamide |
| Application: | Potent, cell-permeable, reversible IKKbeta inhibitor |
| CAS | 354811-10-2 |
| MW: | 261.3 D |
From 87.00€
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