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Item number: Cay14664-10

NS 6180 is an inhibitor of the intermediate-conductance calcium-activated potassium channel 3.1 (IKCa1/KCa3.1, IC50 = 9.4 nM in HEK293 cells expressing the human channel). It inhibits hyperpolarization of human, mouse, and rat erythrocytes induced by the calcium ionophore A23187 (Cay-11016) (IC50s = 14, 15, and 9...

Keywords:	4-[[3-(trifluoromethyl)phenyl]methyl]-2H-1,4-benzothiazin-3(4H)-one
Application:	KCa3.1 channel blocker
CAS	353262-04-1
MW:	323.3 D

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