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Item number: Cay21800-1

MM-11253 is a synthetic, conformationally restricted retinoid that acts as a selective antagonist of retinoic acid receptor gamma (RARgamma). It dose-dependently blocks the ability of RARgamma-selective agonists, but not retinoic acid (all-trans retinoic acid, Cay-11017), to inhibit the growth of oral squamous cell...

Keywords:	6-[2-(5,6,7,8-tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)-1,3-dithiolan-2-yl]-2-naphthalenecarboxylic acid
Application:	RARgamma antagonist
CAS	345952-44-5
MW:	462.7 D

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MM 11253

Item number: TGM-T23005-100mg

Description: MM 11253 is a RARgamma antagonist with IC50 of 44nM. Target: Retinoid Receptor. Smiles: CC1(C)CCC(C)(C)c2cc(ccc12)C1(SCCS1)c1ccc2cc(ccc2c1)C(O)=O. References: M I Dawson, et al. Retinoic acid (RA) receptor transcriptional activation correlates with inhibition of...

Keywords:	MM-11253
CAS	345952-44-5
MW:	462.67 D

From 34.00€ *

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