Description: MTIC is the active metabolite of Temozolomide (TMZ) with anticancer and antitumor activity and is used in the study of melanoma.3'-Sialyllactose (3'-SL) sodium is a prebiotic with anti-inflammatory activity. Target: Drug Metabolite. Smiles: CN\N=N\c1[nH]cnc1C(N)=O. References: Kim HK, et al....

MTIC is a DNA alkylating agent, an active metabolite of dacarbazine (DTIC, Cay-21877), and an active degradation product of temozolomide (Cay-14163). MTIC is cytotoxic to L-cells and decreases thymidine and uridine uptake by 55 and 65%, respectively, when used at a concentration of 1 mM. It is also cytotoxic to TLX5...