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COVID-19 Research
Auranofin
Item number: Cay15316-25
Auranofin is a gold-thiol complex with diverse biological activities. It inhibits thioredoxin reductase (IC50 = 0.2 µM), increases oxidation of mitochondrial peroxiredoxin 3 (PRDX3), and induces apoptosis in Jurkat T cells. Auranofin reduces the production of IL-6 and activation of JAK1 and JAK2, as well as inhibits...
| Keywords: | NSC 321521, Ridauragold thiol, SKF 39162, [1-(thio-kappaS)-beta-D-glucopyranose 2,3,4,6-tetraacetato](triethylphosphine)-gold |
| Application: | Thioredoxin reductase inhibitor |
| CAS | 34031-32-8 |
| MW: | 678.5 D |
From 74.00€
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COVID-19 Research
Auranofin
Item number: AG-CR1-3611-M025
White to off-white solid. Soluble in DMSO or 100% ethanol. Insoluble in water. Anti-inflammatory and anti-arthritic agent. Represses the activation of the NLRP3/IL-1beta pathway, Inhibitor of 5-lipoxygenase in human neutrophils, IKB kinase (IKK) by modifying Cys-179 of the IKKbeta subunit 5, Potent thioredoxin...
| Keywords: | 1-Thio-beta-D-glucopyranosatotriethylphosphine gold-2,3,4,6-tetra- acetate, NSC 321521, SKF 39162 |
| Application: | Antiinflammatory agent |
| CAS | 34031-32-8 |
| MW: | 678,5 D |
From 61.00€
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