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Aurora kinase inhibitor-2
Item number: TGM-T9040-100mg
Description: Aurora kinase inhibitor-2 (IUN-70219) is a cell-permeable anilinoquinazoline that inhibit the activity of Aurora A (IC50 = 0.39 M). Target: Aurora Kinase. Smiles: COc1cc2ncnc(Nc3ccc(NC(=O)c4ccccc4)cc3)c2cc1OC. References: Heron N M , Anderson M , Blowers D P , et al. SAR and inhibitor complex structure...
| Keywords: | Aurora Kinase Inhibitor II, IUN-70219 |
| Application: | Aurora kinase inhibitor |
| CAS | 331770-21-9 |
| MW: | 400.43 D |
From 98.00€
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Aurora Kinase Inhibitor II
Item number: Cay17541-1
The Aurora kinases are a family of serine/threonine kinases that are key regulators of mitosis and cytokinesis. Aurora kinase inhibitor II is a cell-permeable anilinoquinazoline that blocks the activity of Aurora A (IC50 = 0.39 µM). In MCF-7 cells, it blocks proliferation with an IC50 value of 1.25 µM.Formal Name:...
| Keywords: | 4-(4'-Benzamidoanilino)-6,7-dimethoxyquinazoline, N-[4-[(6,7-dimethoxy-4-quinazolinyl)amino]phenyl]-benzamide |
| Application: | AURKA inhibitor |
| CAS | 331770-21-9 |
| MW: | 400.4 D |
From 84.00€
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