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Item number: TGM-T84947-10mg

Description: Desethoxy quetiapine, an active metabolite of the atypical antipsychotic quetiapine, primarily forms through the action of the cytochrome P450 (CYP) isoform CYP3A5. This compound binds to dopamine D2 receptors with an IC50 value of 1,330 nM. In vivo, desethoxy quetiapine at dosages of 20 and 40 mg/kg...

Keywords:	O-Desalkylquetiapine
Application:	Quetiapine active metabolite
CAS	329218-14-6
MW:	412.38 D

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Desethoxy Quetiapine (hydrochloride)

Item number: Cay35410-10

Desethoxy quetiapine is an active metabolite of the atypical antipsychotic quetiapine (Cay-14152). It is formed from quetiapine primarily by the cytochrome P450 (CYP) isoform CYP3A5 and binds to dopamine D2 receptors (IC50 = 1,330 nM). Desethoxy quetiapine (20 and 40 mg/kg) reduces climbing induced by the dopamine...

Keywords:	O-Desalkylquetiapine, 4-dibenzo[b,f][1,4]thiazepin-11-yl-1-piperazineethanol, dihydrochloride
Application:	Quetiapine active metabolite
CAS	329218-14-6
MW:	412.4 D

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