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AG-13958
Item number: Cay41352-1
AG-13958 is an antagonist of VEGFR2 (Ki = 0.3 nM). It inhibits VEGF-induced proliferation of human umbilical vein endothelial cells (HUVECs, IC50 = 0.31 nM).Formal Name: N-[2-fluoro-5-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]amino]phenyl]-1,3-dimethyl-1H-pyrazole-5-carboxamide. CAS Number: 319460-94-1....
| Keywords: | N-[2-fluoro-5-[[3-[(1E)-2-(2-pyridinyl)ethenyl]-1H-indazol-6-yl]amino]phenyl]-1,3-dimethyl-1H-pyrazole-5-carboxamide |
| Application: | VEGFR2 antagonist |
| CAS | 319460-94-1 |
| MW: | 467.5 D |
From 88.00€
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AG-13958
Item number: TGM-T7493-100mg
Description: AG-13958 (AG-013958) (AG-013958), a potent VEGFR tyrosine kinase inhibitor, for the treatment of age-related macular degeneration. Target: VEGFR. Smiles: Cc1cnn(C)c1C(=O)Nc1cc(Nc2ccc3c(\C=C\c4ccccn4)n[nH]c3c2)ccc1F. References: Barakat M R , Kaiser P . VEGF inhibitors for the treatment of neovascular...
| Keywords: | AG-013958 |
| Application: | FLT/TYK receptor inhibitor |
| CAS | 319460-94-1 |
| MW: | 467.5 D |
From 98.00€
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AG13958
Item number: SYN-1004-M001
Soluble in DMSO. AG13958 is a VEGF inhibitor that was in clinical development for treatment of age-related macular degeneration (AMD). The drug displays low water solubility and so far in trials delivery has been difficult needing direct injection to be truly effective and it varied by the species used because of...
| Keywords: | AG-13958 |
| Application: | FLT/TYK receptor inhibitor |
| CAS | 319460-94-1 |
| MW: | 467,5 D |
From 385.00€
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