Nocodazole is an antimitotic agent. It increases tubulin GTP hydrolysis four-fold and induces tubulin depolymerization. Nocodazole (4 µg/ml) halts the cell cycle in the mitotic phase and synchronizes WI38 cells in the G2/M phase. It also decreases neuronal mitochondrial transport and density in a transgenic...

Description: Nocodazole (Oncodazole) is a reversible inhibitor of microtubule polymerization and an inhibitor of Bcr-Abl. Nocodazole has antitumor activity, blocks the cell cycle and induces apoptosis. Target: Bcr-Abl, Microtubule Associated, Autophagy, Apoptosis, CRISPR/Cas9. Smiles:...

Microtubule inhibitor, Antitumor compound, Mitosis inhibitor, Arrests the cell cycle at G2/M phase, Promotes tubulin depolymerization, Induces fragmentation of the Golgi complex, Inhibits the T cell antigen receptor, Stimulates the intrinsic GTPase activity of tubulin, Activates the JNK/SAPK signaling pathway,...

Nocodazole is a microtuble-active drug.

Nocodazole, an inhibitor of microtubule formation, was found to greatly inhibit cell division around the mound stage as well as during the vegetative growth phase, when applied to exponentially growing Ax-2 cells. Mitotic arrest of cells with nocodazole can be used to study phosphorylation of microtubule-associated...