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IU1
Item number: TGM-T6107-100mg
Description: IU1(IC50=4.7 µ M), a reversible, specific human USP14 proteasome inhibitor, can penetrate the cell. Target: DUB, Autophagy. Smiles: Cc1c(ccn1-c1ccc(F)cc1)C(=O)CN1CCCC1. References: Byung-Hoon L, et al. Nature, 2010, 467(7312), 179-184.
| Application: | Deubiquitination inhibitor |
| CAS | 314245-33-5 |
| MW: | 300.37 D |
From 53.00€
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IU1
Item number: Cay10617-10
Polybiquitinylation designates proteins for proteasomal degradation. USP14 is one of several deubiquitinating enzymes (DUBs) responsible for shortening proteasome-bound ubiquitin chains, which is known to antagonize the degradation of ubiquitin-protein conjugates. IU1 is a reversible, small molecule inhibitor of...
| Keywords: | 1-[1-(4-fluorophenyl)-2,5-dimethyl-1H-pyrrol-3-yl]-2-(1-pyrrolidinyl)-ethanone |
| Application: | Deubiquitination inhibitor |
| CAS | 314245-33-5 |
| MW: | 300.4 D |
From 52.00€
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