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Item number: TGM-T3538-100mg

Description: Sufugolix (TAK-013) is a potent and orally available luteinizing hormone-releasing hormone (LHRH) receptor antagonist. Target: LHRH. Smiles: CONC(=O)Nc1ccc(cc1)-c1sc2n(Cc3c(F)cccc3F)c(=O)n(-c3ccccc3)c(=O)c2c1CN(C)Cc1ccccc1. References: Sasaki S, et al. Discovery of a thieno[2,3-d]pyrimidine-2,4-dione...

Keywords:	TAK-013
Application:	Gonadotropin-releasing hormone receptor (GnRHR) antagonist
CAS	308831-61-0
MW:	667.72 D

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Sufugolix

Item number: Cay27996-1

Sufugolix is a gonadotropin-releasing hormone (GnRH) receptor antagonist (IC50 = 0.1 nM). Sufugolix inhibits GnRH-induced arachidonic acid (Cay-90010, Cay-90010.1, Cay-10006607) release in CHO cells expressing human recombinant or monkey recombinant GnRH (IC50s = 0.1 and 10 nM, respectively), but not the rat GnRH...

Keywords:	TAK-013,...
Application:	Gonadotropin-releasing hormone receptor (GnRHR) antagonist
CAS	308831-61-0
MW:	667.7 D

From 48.00€ *

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