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Item number: TGM-T6681-100mg

Description: STF-083010 is a selective inhibitor of the IRE1alpha endonuclease. Target: IRE1. Smiles: O=C1C=Cc2ccccc2\C1=C\NS(=O)(=O)c1cccs1. References: Papandreou l, et al. Blood. 2011, 117(4), 1311-1314.

Keywords:	STF083010
Application:	ERN1 endonuclease inhibitor
CAS	307543-71-1
MW:	317.38 D

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STF-083010

Item number: Cay17370-5

STF-083010 is an inhibitor of the IRE1/XBP1 pathway, blocking IRE1 endonuclease activity without affecting its kinase activity after endoplasmic reticulum (ER) stress both in vitro and in vivo. STF-083010 (60 µM) reduces the splicing of XBP1 by IRE1 in the presence of thapsigargin (Cay-10522), an ER stress inducer....

Keywords:	IRE1 Inhibitor I, N-[(2-hydroxy-naphthalenyl)methylene]-2-thiophenesulfonamide
Application:	ERN1 endonuclease inhibitor
CAS	307543-71-1
MW:	317.4 D

From 60.00€ *

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