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Item number: Cay39615-1

ARN25062 is a derivative of ARN22089, an inhibitor of the protein-protein interaction between Cdc42 and p21-activated kinase (PAK). It inhibits the proliferation of SKM28, SK-MEL-3, WM3248, and A375 melanoma cells (IC50s = 6.1, 4.6, 9.3, and 5.1 µM, respectively) and SW480 colon cancer cells (IC50 = 5.9 µM)....

Keywords:	6-phenyl-2-(4-piperidinyl)-N-[3-(trifluoromethyl)phenyl]-4-pyrimidinamine
Application:	ARN22089 (Cdc42--p21-activated kinase interaction inhibitor) derivative
CAS	3036492-85-7
MW:	398.4 D

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