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Item number: Cay38517-10

Zapnometinib is a MEK inhibitor (IC50 = 5.73 nM) and an active metabolite of CI-1040 (Cay-11580). It reduces viral titers in A549 and MDCK cells infected with influenza A (EC50s = 6.356 and 4.498 µM, respectively). Zapnometinib (50 mg/kg per day) increases survival in H1N1pdm09 influenza A-infected mice.Formal Name:...

Keywords:	ATR-002, PD 0184264, 2-[(2-chloro-4-iodophenyl)amino]-3,4-difluoro-benzoic acid
Application:	MEK inhibitor
CAS	303175-44-2
MW:	409.6 D

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