Description: Novobiocin is an orally active and potent antibiotic.Novobiocin is a DNA gyrase inhibitor and heat shock protein 90 (Hsp90) antagonist with inhibitory effects on gyrase and Hsp90. Novobiocin has anti-positive activity and can be used to study highly resistant pneumococcal infections. Target: Antibiotic,...

Novobiocin is an aminocoumarin antibiotic that is produced by Streptomyces niveus. Along with other aminocoumarin antibiotics, novobiocin is a very potent inhibitor of bacterial DNA gyrase. It works by targeting the GyrB subunit of the enzyme involved in energy transduction. Novo-TRX is Texas Red-labeled novobiocin,...