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Dasatinib
Item number: TGM-T1448-50mg
Description: Dasatinib (BMS-354825) is an orally active, ATP-competitive tyrosine kinase inhibitor that targets Src and Bcr-Abl (Ki=16/30 pM), with antitumor activity, used in the treatment of leukemia and lymphoma. Target: c-Kit, Autophagy, Bcr-Abl, Apoptosis, Src. Smiles:...
| Keywords: | BMS-354825 |
| Application: | Targets abelson tyrosine-protein kinase 1 [EC:2.7.10.2] (ABL1) |
| CAS | 302962-49-8 |
| MW: | 488.01 D |
From 38.00€
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Dasatinib
Item number: Cay11498-10
Dasatinib is a potent inhibitor of the non-receptor tyrosine kinases Abl and Src as well as other members of the Src family. It is effective at sub-nanomolar concentrations, inhibiting Src, Abl, and Lck with IC50 values of 0.05, 0.5, and 0.4 nM, respectively. At nanomolar concentrations, dasatinib also blocks the...
| Keywords: | BMS 354825, Sprycel,... |
| Application: | Tyrosine kinase inhibitor |
| CAS | 302962-49-8 |
| MW: | 488 D |
From 44.00€
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Dasatinib
Item number: AG-CR1-3540-M010
Dasatinib is a potent multi-kinase inhibitor of the non-receptor tyrosine kinases Abl and Src as well as other members of the Src family. Dasatinib is a highly potent pan-Src/Bcr-Abl inhibitor (Ki values are 16 and 30 pM, respectively). It is also effective at sub-nanomolar concentrations, inhibiting Lyn, Fyn,...
| Keywords: | BMS-354825, Sprycel,... |
| Application: | Tyrosine kinase inhibitor |
| CAS | 302962-49-8 |
| MW: | 488 D |
From 33.00€
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Dasatinib
Item number: LKT-D023721.100
Multikinase inhibitor.
| Keywords: | BMS354825, BMS-354825, Sprycel |
| Application: | Bcr-Abl tyrosine kinase / c-KIT / src inhibitor, Eph receptor A2 antagonist, PDGFRB inhibitor |
| CAS | 302962-49-8 |
| MW: | 488.01 D |
From 66.00€
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