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Item number: TGM-T3463-100mg

Description: ACC-789 (NVP-ACC789 (ZK202650), ZK-202650) is an effective, specific and orally active inhibitor of the VEGF receptor tyrosine kinases. Target: VEGFR, PDGFR. Smiles: Cc1ccc(Nc2nnc(Cc3ccncc3)c3ccccc23)cc1Br. References: Tille JC, et al. Vascular endothelial growth factor (VEGF) receptor-2 antagonists...

Keywords:	ZK202650, ACC-789
Application:	VEGFR inhibitor
CAS	300842-64-2
MW:	405.29 D

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NVP-ACC789

Item number: Cay23458-1

NVP-ACC789 is an inhibitor of VEGF receptor tyrosine kinases (VEGFRs, IC50s = 0.38, 0.02, 0.18, and 0.23 µM for human VEGFR1, 2, 3, and mouse Vegfr2, respectively). It is selective for VEGFRs over FGFRs and PDGFRalpha (IC50s = >10 µM) but has activity at PDGFRbeta (IC50 = 1.4 µM) in an enzyme assay. NVP-ACC789...

Keywords:	N-(3-bromo-4-methylphenyl)-4-(4-pyridinylmethyl)-1-phthalazinamine
Application:	VEGFR inhibitor
CAS	300842-64-2
MW:	405.3 D

From 60.00€ *

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