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RS 504393
Item number: TGM-T5384-100mg
Description: RS 504393 is a highly selective CCR2 chemokine receptor antagonist (IC50s: 89 nM and > 100 µM for human recombinant CCR2 and CCR1). Target: CCR. Smiles: Cc1oc(nc1CCN1CCC2(CC1)OC(=O)Nc1ccc(C)cc21)-c1ccccc1. References: Mirzadegan T, et al. Identification of the binding site for a novel class of CCR2b...
| Application: | CCR2 chemokine receptor antagonist |
| CAS | 300816-15-3 |
| MW: | 417.5 D |
From 43.00€
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RS 504393
Item number: Cay17330-1
RS 504393 is a selective antagonist of the MCP-1 receptor CCR2 (IC50s = 89 nM and >100 µM for CCR2 and CCR1, respectively). It has been shown to inhibit MCP-1-stimulated chemotaxis (IC50 = 330 nM) and ischemia-reperfusion injury in kidneys.Formal Name:...
| Keywords: | 6-methyl-1'-[2-(5-methyl-2-phenyl-4-oxazolyl)ethyl]-spiro[4H-3,1-benzoxazine-4,4'-piperidin]-2(1H)-one |
| Application: | CCR2 chemokine receptor antagonist |
| CAS | 300816-15-3 |
| MW: | 417.5 D |
From 61.00€
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