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(±)-Norcantharidin
Item number: TGM-T5656-100mg
Description: (±)-Norcantharidin (Endothall anhydride) is a synthetic anticancer compound which is a dual inhibitor for c-Met and EGFR in human colon cancers. Target: c-Met/HGFR, EGFR. Smiles: O=C1OC(=O)C2C3CCC(O3)C12. References: Qiu P , Wang S , Liu M , et al. Norcantharidin Inhibits cell growth by suppressing the...
| Keywords: | Endothall anhydride, Norcantharidin |
| Application: | PP1 / PP2A inhibitor |
| CAS | 29745-04-8 |
| MW: | 168.15 D |
From 38.00€
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Norcantharidin
Item number: Cay28457-5
Norcantharidin is a demethylated form of the protein phosphatase 1 (PP1) and PP2A inhibitor cantharidin (Cay-14589) and a PP1 and PP2A inhibitor (IC50s = 9 and 3 µM, respectively). It induces cell cycle arrest at the G2/M phase and apoptosis in HepG2, Hep3B, and Huh7 human hepatoma cell lines when used at a...
| Keywords: | Demethylcantharidin, NCTD, NSC 59023, (3aR,4S,7R,7aS)-rel-hexahydro-4,7-epoxyisobenzofuran-1,3-dione |
| Application: | PP1 / PP2A inhibitor |
| CAS | 29745-04-8 |
| MW: | 168.1 D |
From 44.00€
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