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Item number: TGM-T24730-100mg

Description: Roslin 2 bromide (Benzylhexamethylenetetramine bromide) is a p53 reactivator that disrupts the binding of FAK and p5, exhibiting anticancer effects. Target: FAK, p53. Smiles: [Br-].C(c1ccccc1)[N+]12CN3CN(CN(C3)C1)C2. References: Learmount J, Callaby R, Taylor M. An observational study of ewe treatments...

Keywords:	Roslin-2, Roslin2, Benzylhexamethylenetetramine bromide
Application:	p53 reactivator, FAK-p53 interaction inhibitor
CAS	29574-21-8
MW:	311.22 D

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Roslin-2

Item number: Cay21985-1

Roslin-2 is a reactivator of p53. Roslin-2 (111, 333, and 1000 µM) impairs the interaction between focal adhesion kinase (FAK) and p53 and restores p53 transcriptional activity. It reverses FAK-mediated suppression of the expression of p53-dependent p21, MDM2, and Bax in wild-type p53 HCT116 colon and MCF-7 breast...

Keywords:	1-(phenylmethyl)-3,5,7-triaza-1-azoniatricyclo[3.3.1.13,7]decane, monobromide
Application:	p53 reactivator, FAK-p53 interaction inhibitor
CAS	29574-21-8
MW:	311.2 D

From 50.00€ *

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