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Item number: Cay30068-1

4-CPPC is an inhibitor of macrophage migration inhibitory factor-2 (MIF-2, IC50 = 27 µM). It is selective for MIF-2 over MIF-1 (IC50 = 450 µM). It inhibits MIF-2, but not MIF-1, binding to CD74 in vitro when used at a concentration of 10 µM. 4-CPPC (5, 10, and 25 µM) inhibits MIF-2-induced ERK1/2 phosphorylation in...

Keywords:	4-(3-carboxyphenyl)-2,5-pyridinedicarboxylic acid
Application:	D-dopachrome decarboxylase (DDT / MIF-2) inhibitor
CAS	29553-70-6
MW:	287.2 D

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