Description: 7-Nitroindazole is a non-selective inhibitor of NOS isoforms in vitro for neuronal nitric oxide synthase showing a 10-fold selectivity for neuronal NOS. Target: NOS. Smiles: [O-][N+](=O)C1=CC=CC2=CNN=C12. References: Vessela V , Rumyana S , Magdalena K B , et al. Selective Nitric Oxide Synthase...

7-NI is a selective inhibitor for the brain nitric oxide synthase (NOS). Yellow orange solid soluble in DMSOStore at 4°CC7H5N3O2MW: 163.1[2942-42-9]

This kit contains four nitric oxide synthase (NOS) inhibitors: 7-NI, L-NMMA, L-NIL, and L-NIO. 7-NI is a selective inhibitor for the brain nitric oxide synthase (NOS). Yellow orange solid soluble in DMSOStore desiccated at 4°CC7H5N3O2MW: 163.1[2942-42-9] L-NMMA (NG-Methyl-L-arginine, acetate salt) competitively...

7-Nitroindazole is a non-selective inhibitor of NOS isoforms in vitro. However, it shows good anti-nociceptive effects in vivo without affecting blood pressure via inhibition of eNOS. The IC50 values for inhibition of rat nNOS, bovine eNOS, and rat iNOS are 0.71, 0.78, and 5.8 µM, respectively.Formal Name:...

A neuronal nitric oxide synthase (nNOS) inhibitor. It enhances amphetamine-evoked release, and kainic acid induced cholinergic neurotoxicity in the rat striatum.