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Ro 90-7501
Ro 90-7501

Item number: TGM-T16773-100mg

Description: Ro 90-7501 is an amyloid beta42 (Abeta42) protofibrillar and TPR-dependent PP5 inhibitor, a novel radiosensitizer for cervical cancer cells, which inhibits ATM phosphorylation, promotes apoptosis, and induces cell-cycle arrest. Ro 90-7501 also exhibits antiviral activity and potential anticancer...
Keywords: RO-90-7501
Application: Abeta42 fibril assembly inhibitor, TLR3 signaling modulator
CAS 293762-45-5
MW: 340.38 D
From 31.00€ *
Review
Ro 90-7501
Ro 90-7501

Item number: Cay18881-5

Ro 90-7501 is a bi-benzimidazole compound that was first found to retard the formation of mature amyloid beta42 fibrils in a cell-based assay. Instead, extended polymeric sheets and fibrillary intermediates of amyloid beta42 accumulated in response to Ro 90-7501 treatment, resulting in reduced cytotoxicity (EC50 = 2...
Keywords: 2'-(4-aminophenyl)-[2,5'-bi-1H-benzimidazol]-5-amine
Application: Abeta42 fibril assembly inhibitor, TLR3 signaling modulator
CAS 293762-45-5
MW: 340.4 D
From 121.00€ *
Review