3 products were found matching "293754-55-9"!
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T0901317
Item number: TGM-T6690-100mg
Description: T0901317 is a potent and selective agonist for both LXR and FXR, with EC50 of ~50 nM and 5 µM, respectively, it inhibits nuclear factor/kappaB (NF/kappaB). Target: Apoptosis, FXR, ROR, Liver X Receptor. Smiles: C(C(F)(F)F)(C(F)(F)F)(O)C1=CC=C(N(S(=O)(=O)C2=CC=CC=C2)CC(F)(F)F)C=C1. References: Repa...
| Application: | Potent, cell permeable, selective LXRalpha / LXRbeta agonist |
| CAS | 293754-55-9 |
| MW: | 481.33 D |
From 33.00€
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T0901317
Item number: Cay71810-10
The Liver X Receptors (LXRalpha and LXRbeta) are nuclear hormone receptors whose native ligands are oxysterols, such as 22(R)-hydroxycholesterol. The LXRs regulate the oxysterol-induced expression of cholesterol 7alpha-hydroxylase, the rate limiting enzyme of classic bile acid synthesis. T0901317 is a potent and...
| Keywords: | N-(2,2,2-trifluoroethyl)-N-[4-[2,2,2-trifluoro-1-hydroxy-1-(trifluoromethyl)ethyl]phenyl]-benzenesulfonamide |
| Application: | LXRalpha agonist, LXRbeta agonist |
| CAS | 293754-55-9 |
| MW: | 481.3 D |
From 55.00€
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T0901317
Item number: AG-CR1-2906-M010
White to off-white solid. Soluble in DMSO, DMF or ethanol (all 50mg/ml). Chemical. CAS: 293754-55-9. Formula: C17H12F9NO3S. MW: 481.3. T0901317 is a potent, cell permeable and selective agonist of LXRalpha and LXRbeta (EC50 of 50nM, Kd values are 7 and 22 nM for LXR-alpha and LXR-beta, respectively), results in...
| Keywords: | TO-901317, T 1317 |
| Application: | Potent, cell permeable, selective LXRalpha / LXRbeta agonist |
| CAS | 293754-55-9 |
| MW: | 481,3 D |
From 33.00€
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