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Item number: Cay38494-1

SZM-1209 is an inhibitor of receptor-interacting serine/threonine kinase 1 (RIPK1). It selectively binds to RIPK1 over RIPK3 (Kds = 85 and >10,000 nM, respectively) and inhibits necrosome formation and phosphorylation of RIPK1 induced by TNF-alpha, SM-164 (Cay-28632), and Z-VAD-FMK in HT-29 cells (EC50 = 22.4 nM)....

Keywords:	N-[5-[[2-[[[4-[(ethylsulfonyl)amino]cyclohexyl]carbonyl]amino]-5-fluoro-6-benzothiazolyl]oxy]-2-fluorophenyl]-3-(trifluoro...
Application:	RIPK1 inhibitor
CAS	2919801-86-6
MW:	696.7 D

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