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Item number: Cay38344-1

STING agonist 12L is an agonist of stimulator of interferon genes (STING). It binds to wild-type STING (IC50 = 1.15 µM), as well as the STING R232, AQ, and Q variants (IC50s = 1.06, 0.61, and 1.12 µM, respectively) and induces reporter gene expression in THP-1 and RAW 264.7 cells (EC50s = 0.38 and 12.94 µM,...

Keywords:	Stimulator of Interferon Genes Agonist 12L, 2-([3,4'-bipyridazine]-6-carboxamido)-4-ethynyl-5-fluorobenzoic acid
Application:	STING agonist
CAS	2913152-30-2
MW:	363.3 D

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