Description: Procyanidin B2 (Proanthocyanidin B2) has vascular protective, anti-diabetic nephropathy, anti-cancer, anti-inflammatory, and antioxidant activities. Procyanidin B2 inhibited NLRP3 inflammasome activation via suppression of AP-1 pathway. Target: NOD, Reactive Oxygen Species. Smiles:...

Procyanidin B2, one of the most representative naturally occurring edible pigments, is usually isolated from the seeds, fruits and leaves of lots of common plants, such as grapes or apples. Procyanidin B2 has numerous bioactivities, including anti-inflammatory, anti-oxidative stress, neuroprotective, lipid...

Procyanidin B2 is a phenol and a dimer of (-)-epicatechin (Cay-11807) that has been found in apple pomace and has diverse biological activities. It inhibits MCF-7 breast cancer cell proliferation (IC50 = 19.2 µM). Procyanidin B2 scavenges 2,2-diphenyl-1-picrylhydrazyl (DPPH, Cay-14805) and superoxide anion radicals...