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Glipizide
Item number: TGM-T1603-1g
Description: Glipizide (CP 28720) is a short-acting, second-generation sulfonylurea with hypoglycemic activity. Target: PPAR, ABC, Potassium Channel. Smiles: S(NC(NC1CCCCC1)=O)(=O)(=O)C2=CC=C(CCNC(=O)C=3C=NC(C)=CN3)C=C2. References: Gribble FM, Ashcroft FM. Metabolism. 2000 Oct,49(10 Suppl 2):3-6.
| Keywords: | K 4024, CP 28720 |
| Application: | Targets ATP-binding cassette subfamily C (CFTR/MRP) member 8 (ABCC8, SUR1) |
| CAS | 29094-61-9 |
| MW: | 445.54 D |
From 40.00€
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Glipizide
Item number: Cay11579-1
Glipizide is a hypoglycemic agent. It inhibits ATP-sensitive potassium (KATP) channels in primary mouse pancreatic beta cells (IC50 = 6.4 nM). Glipizide induces insulin release from isolated rat pancreatic tissue with an EC50 value of 40 nM. Dietary administration of glipizide (5 mg/kg per day for 10 days) increases...
| Keywords: | CP 28720, K 4024, TK 1320, N-[2-[4-[[[(cyclohexylamino)carbonyl]amino]sulfonyl]phenyl]ethyl]-5-methyl-2-pyrazinecarboxamide |
| Application: | Sulfonylurea receptor agonist, Hypoglycemic agent |
| CAS | 29094-61-9 |
| MW: | 445.5 D |
From 40.00€
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Glipizide
Item number: LKT-G4634.1
An oral hypoglycemic agent that enhances insulin secretion by inhibiting its metabolic clearance. It blocks ATP-dependent K channels in pancreatic b cells and brain GABA containing neurons resulting in insulin release.
| Application: | Hypoglycemic agent |
| CAS | 29094-61-9 |
| MW: | 445,54 D |
From 94.00€
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