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Item number: Cay23385-5

TRAM-34 is a membrane-permeable inhibitor of the intermediate-conductance calcium-activated potassium channel (IKCa1/KCa3.1). It blocks IKCa1 (Kds = 20 and 25 nM for the cloned and native channel in COS-7 cells and human T lymphocytes, respectively) with 200- to 1,500-fold selectivity for IKCa1 over Kv (Kv1.1-Kv1.5,...

Keywords:	1-[(2-chlorophenyl)diphenylmethyl]-1H-pyrazole
Application:	Membrane-permeable KCNN4 inhibitor
CAS	289905-88-0
MW:	344.8 D

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