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IBMX
Item number: Cay13347-100
IBMX is a widely-used non-specific inhibitor of cyclic AMP and cyclic GMP phosphodiesterases (PDEs) (IC50 = 19, 50, 18, 13, 32, 7, and 50 µM for PDE1, PDE2, PDE3, PDE4, PDE5, PDE7, and PDE11, respectively). PDE8A, PDE8B, and PDE9 are insensitive to IBMX. By inhibiting PDEs, IBMX increases cellular cAMP and cGMP...
| Keywords: | 1-Methyl-3-Isobutylxanthine, Isobutylmethylxanthine, NSC 165960, SC-2964,... |
| Application: | PDE inhibitor |
| CAS | 28822-58-4 |
| MW: | 222.3 D |
From 52.00€
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IBMX
Item number: TGM-T1713-100mg
Description: IBMX (Methylisobutylxanthine) is a broad-spectrum phosphodiesterase (PDE) inhibitor with inhibitory activity against PDE3, PDE4, and PDE5 (IC50=6.5/26.3/31.7 µM). IBMX enhances the intracellular cAMP level. Target: PDE. Smiles: CC(C)Cn1c2[nH]cnc2c(=O)n(C)c1=O. References: Wei Y, et al. Angiotensin II...
| Keywords: | 3-Isobutyl-1-methylxanthine, 1-Methyl-3-Isobutylxanthine, Isobutylmethylxanthine, Methylisobutylxanthine |
| Application: | Phosphodiesterase inhibitor |
| CAS | 28822-58-4 |
| MW: | 222.24 D |
From 34.00€
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IBMX
Item number: AG-CR1-3512-M500
Cell permeable protein kinase C (PKC) inhibitor. Inhibits also protein kinase A (PKA).
| Keywords: | 3-Isobutyl 1-methylxanthine, NSC 165960, EINECS 249-259-3 |
| Application: | Phosphodiesterase inhibitor |
| CAS | 28822-58-4 |
| MW: | 222,3 D |
From 121.00€
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